What is the longest-running American animated series?

The Simpsons is an American animated sitcom created by Matt Groening for the Fox Broadcasting Company. The series is a satirical depiction of American life, epitomized by the Simpson family, which consists of Homer, Marge, Bart, Lisa, and Maggie. The show is set in the fictional town of Springfield and parodies American culture and society, television, and the human condition. Since its debut on December 17, 1989, 740 episodes of the show have been broadcast. It is the longest-running American animated series, the longest-running American sitcom, and the longest-running American scripted primetime television series, both in terms of seasons and the number of episodes.

Source: Wikipedia